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Clinical

Covid treatment trial to look at inhaled corticosteroid

The inhaled corticosteroid budesonide has been added to Oxford University’s PRINCIPLE trial looking at potential Covid-19 treatments that prevent hospital admission.

HRT: breast cancer risk depends on formulation and duration of use

The risk that women using hormone replacement therapy (HRT) will develop breast cancer depends on the formulation and duration of use, a new analysis suggests.

Use of hormonal contraceptives linked to reduced asthma risk

A study claims the use of hormonal contraceptives may reduce the risk of severe asthma in women.

Pharmacist interventions prevent pregnancy after EHC

Pharmacist interventions result in a significant increase in effective use of a contraceptive pill following emergency hormonal contraception.

Ridge: Only use dexamethasone for oxygen patients

Dexamethasone should be used to treat patients with critical or severe Covid-19 but not patients with ‘non-severe’ illness, Keith Ridge says. 

Most side effects of statins down to 'nocebo effect'

Most of the side-effects people suffer after taking statins are due to their negative associations with the drug, researchers have found.  

Aspirin could protect against severe Covid-19

Taking aspirin may reduce the need for admission to an intensive care unit (ICU) and in-hospital mortality among people hospitalised with Covid-19.

Covid-19 antibody response wanes over time

Over three months the proportion of people who tested positive for antibodies declined by 26.5 per cent.

Intranasal spray may offer Covid protection, study suggests

An intranasal spray product using a mucoadhesive gel may offer some protection against coronavirus infection, new research suggests.

Once-promising Covid drug has ‘little to no survival impact’

Remdesivir – hailed in May as a potential breakthrough – has little impact on survival rates for patients hospitalised with the virus, says WHO.

Over-50s suffering with loneliness at risk of diabetes

KCL study shows a strong relationship between loneliness and the later onset of type 2 diabetes

Discovery of four Covid-19 risk groups could help guide treatment

A risk identification tool uses the groupings to help clinical staff choose the best course of treatment for patients.

‘Immediate NHS action’ to safeguard hydrocortisone after Covid study

Seriously ill coronavirus patients have a better than 90 per cent chance of improved recovery when given a seven-day course of hydrocortisone.

Children with gastro problems should be tested for Covid-19

Researchers have called for children with gastrointestinal symptoms to be tested for Covid-19.

Clozapine toxicity in spotlight after two Coroners reports

Monitoring blood concentrations of clozapine for toxicity is now advised in certain clinical situations says MHRA.

Bipolar disorder tablets to be discontinued

Priadel 200mg and 400mg modified release tablets are to be discontinued, with all remaining supplies expected to run out by April of next year. 

Hypertension treatments could improve Covid survival rates

People with high blood pressure have a better chance of surviving Covid-19 if they are taking hypertension medications, research shows. 

Value of statins in the elderly confirmed

Starting statins reduces the risk of all-cause and cardiovascular mortality among people aged 75 years and older, a new study finds. 

Benefits of steroids in inhalers outweighs risk say researchers

The advantages of using inhalers and nebulisers containing steroids outweigh the risks, claim researchers.   

Most vulnerable children no longer need to shield

Independent evidence from RCPCH shows the risk of serious illness for children and young people is low.

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